Influence of repeated stress exposures with hypoxia intolerance on rats oxidized proteins and lipoperoxidation shifts

: Rarely repeated episodes of immobilization stress led to misbalance between pro oxidant and antioxidant systems. So in the brain, kidneys, spleen we observed elevation of oxidized proteins level. In contrast, in the thymus and bone marrow the protein carbonilation was attenuated. In the liver, oxidized protein level remained unchanged. Simultaneously the level of liver lipoperoxidation was increased. These shifts were accompanied with attenuation of catalase activity in the liver and elevation of xanthine oxidase activity in the spleen and erythrocytes.