Isolation and Characterization of New Bufadienolides from Urginea indica

2014 
In the course of phytochemical study of the methanolic extract of the bulb of Urginea indica, nine compounds were isolated from the chloroform soluble fraction. In addition to four bufadienolides, viz. scillaridine (1), 12β-hydroxy scillaridine (2), 5α-4,5-dihydro-8β-hydroxy scillicyanosidin (3), 14β-hydroxybufa-20, 22-dienolide-3-O-α-L-thevetoside (4); three steroids: stigmasterol, β-sitosterol and β-sitosterol3-O-β-D-glucoside; and two waxy components: lauric acid and pentatricontanol were isolated through column chromatography. Scillaridine (1) have been isolated for the first time from the bulb of the title plant. Compounds (2-4) are new and are being reported for the first time. The compounds were identified on the basis of spectral (IR, 1 H NMR, 13 C NMR and Mass) data.
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