Kind of amphipathic polysaccharide - folate conjugates of photosensitive drug carrier and its preparation method of nano

The present invention provides a polysaccharide - Nano photosensitive drug and preparation method folate conjugates of a carrier, the active ingredient comprises a photosensitive drug nano-particles and a solvent, the active ingredient particles are core-shell structure, the core is a photosensitive drugs, the housing amphipathic polysaccharide - folate conjugates, the amphipathic polysaccharide - amino and carboxyl groups of folate folate conjugate is carboxy polysaccharide or polysaccharide derivatized to form derivatized by formation of a connection is formed. The nano good optical stability in vivo photosensitizing drug, polysaccharide - very good biocompatibility folate carrier; and the nano photosensitive drug subject to certain wavelengths of the laser irradiation, no damage to normal skin, and by treatment to eradicate photothermal tumors. The nano photosensitizing drug treatment good did the integration of the tumor.