Optimization and Co-simulation of an Implantable Telemetry System by Linking System Models to Nonlinear Circuits

This chapter presents a platform for modeling, design, optimization, and co-simulation of mixed-signal systems using the SystemC-AMS standard. The platform is based on a bottom-up design and top-down simulation methodologies. In the bottom-up design methodology, an optimizer is inserted to perform a knowledge-aware optimization loop. During the process, a PEANO trajectory is applied for global exploration and the Nelder–Mead simplex optimization method is applied for local refinement. The authors introduce an interface between system-level models and their circuit-level realizations in the proposed platform. Moreover, a transient simulation scheme is proposed to simulate nonlinear dynamic behavior of complete mixed-signal systems. The platform is used to design and verify a low-power CMOS voltage regulator for an implantable telemetry system.