TORP–ZIEGLER CYCLIZATION IN THE SYNTHESIS OF 3-AMINO-4-CYANOPYRROLE DERIVATIVES

Polyfunctional derivatives of 3-aminopyrrole have been synthesized from several substituted β–enamino nitriles using Torp–Ziegler cyclization. These compounds are starting materials for further conversions, particularly for the synthesis of pyrrolo[3,2- d ]- and pyrrolo[3,4- d ]pyrimidines. Authors: S. A. Ryndina, A. V. Kadushkin, N. P. Solov'eva, and V. G. Granik. English Translation in Chemistry of Heterocyclic Compounds , 2000, 36 (12), pp 1409-1420 http://link.springer.com/article/10.1023/A%3A1017566212124