Microelectrode Recording in Neurosurgical Patients

Microelectrode recording (MER) is used to localize and map deep brain structures during neurosurgical procedures and has been a fruitful technique in human neuroscience research. In this chapter, we briefly review the biophysical principles of MER, discuss the use of the technique for targeting as it relates to movement disorders, and conclude with a comparison of the accuracy obtained with MER and with direct targeting with imaging.