Clinical research on percutaneous endoscopic gastrostomy and percutaneous endoscopic jejunostomy without pain at bedside in critical patients

Objective:To investigate the effects of critical patients who were treated with percutaneous endoscopic gastrostomy(PEG)or percutaneous endoscopic jejunostomy(PEJ)with propofol at bedside.Methods:Tirty-eight patients,who were admitted in the ICU of the first affiliated hospital of the Chongqing medical university between August 2006 and December 2008,were randomly divided into P-group (propofol group)and DM-group.(diazepam combined with midazolam group).Electrocardio waveform,breath(Br),SPO2 and blood pressure were monitored and recorded from 10 min before operation to the time with the patients'Ramsay≤Ⅱafter operation (postoperative monitoring≥10min).And recorded the persistence time of operation,awaken time and subjective anamnesis were recorded at 30min after operation.Results:In the operation,the heart rate(HR)in P-group was(72.20±8.96)/min,which was significantly decreased compared with DM-group.The Br was(16.72±8.46)/min in P-group during operation,which was significantly decreased compared with DM-group,and the SPO2 in P-group was(94.87±3.52)%,which was significantly increased compared with DM-group(P0.05).At 10 min after operation,the heart rat(eHR)in P-group was(73.89±10.42)/min,which was significantly lower compared with DM-group;the systolic blood pressure(SBP)in P-group was(117.63±8.02)mmHg which was significantly lower compared with DM-group and the SPO2 of P-group was(98.76±1.04)%which was significantly higher compared with DM-group(P0.05).The persistence time of operation(26.83±5.84)min which was signifi cantlyshorter compared with DM-group(P0.05).The awaken time of P-group was(7.62±2.47)min,which was significantly quicker compared with DM-group(P0.05).The adverse effects inoperation,including restlessness,bucking nausea and vomitting,were significantly not so many in P-group as DM-group(P0.0 And the painful anamnesis to the operation of P-group was significantly not so many as DM-group(P0.05).Conclusion:It was satis to apply propofol for PEJ/PEG without causing pain in critical patients.Propofol could be regarded as the leader ancillary drug in treatment.And it could lessen the harmful stimulus of the operation on the patients,thereby it is helpful lessen the uncalled-for st reactions.