Copper-Catalyzed Regioselective Sulfenylation of Thiazolo[3,2-b]-1,2,4-triazoles with Thiols

A simple and useful protocol was developed for the regioselective copper-catalyzed direct sulfenylation of thiazolo[3,2- b ]-1,2,4-triazoles with thiols. The reaction shows broad functional-group tolerance and provides rapid access to sulfenylated thiazolo[3,2- b ]-1,2,4-triazoles in moderate to good yields.