Decreased risk of developing cancer in subjects carrying SLC52A3 rs13042395 polymorphism: proof from a meta-analysis

Aim: This study aimed to conduct a meta-analysis to explore the association between SLC52A3 rs13042395 polymorphism and cancer risk. Materials & methods: A comprehensive literature search was performed to confirm the relationship evaluated using STATA 12.0 software. Results: Overall, SLC52A3 rs13042395 C>T polymorphism was associated with cancer risk in two genetic models (TT vs CC: odds ratio: 0.86; 95% CI: 0.80–0.93; p T polymorphism might be a potential biomarker for cancer susceptibility.