Identification of the familial cylindromatosis tumour-suppressor gene
2000
Familial cylindromatosis (MIM 132700) is an autosomal domi-nant predisposition to multiple neoplasms of the skinappendages. The tumours (known as cylindromas because oftheir characteristic microscopic architecture) are believed to arisefrom or recapitulate the appearance of the eccrine or apocrinecells of the skin that secrete sweat and scent, respectively
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