Absolute dose measurements for lung gated delivery stereotactic body radiation therapy

2021 
Abstract Purpose To evaluate absolute dose between phase- and amplitude-gated modes for lung stereotactic body radiation therapy (SBRT), using the moving targets developed in-house. Methods The moving targets were developed in-house, allowing measurements of absolute dose using Semiflex ion chamber, Pinpoint ion chamber and microDiamond detector. 24 plans were generated in the Pinnacle 16.2 treatment planning system (TPS). 720 partial dynamic conformal arcs (DCA), 120 for phase- and 120 for amplitude-gated mode per detector, were performed to compare dose discrepancy (planned vs measured doses), for all detectors. Single fraction of 15 Gy was delivered with TrueBeam Novalis STx, triggered on the stable phases (phase-gated mode) or near the end-exhalation (amplitude-gated mode), for a breathing period ranging from 2 s to 7 s, using flattened filter free beams (FFF). Results The lowest discrepancy between measured and planned dose was obtained using the microDiamond detector in the phase-gated −0.1 (−0.2 to 0) % and −0.3 (−0.4 to −0.1) % in amplitude-gated mode (p  Conclusion Detectors with low discrepancy, PinPoint ion chamber and microDiamond detectors, can be used in routine quality assurance for lung gated delivery in SBRT treatment, for commercial phantom as for phantom developed in-house.
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