Genetic screening in gamete donation: Recommendations from SEF, ASESA, AEBM-ML, ASEBIR and AEGH

Abstract Recommendations are made for the genetic screening of gamete donors. These recommendations are the result of the consensus reached by a work group consisting of representatives from the Spanish Fertility Society, the Spanish Association of Andrology, the Spanish Association of Medical Biopathology and Laboratory Medicine, the Association for the Study of Reproductive Biology and the Spanish Association of Human Genetics and were subsequently reviewed and approved by the executive boards of each of these associations. This document describes 2 types of genetic screening: a basic mandatory screening of all donors and an extended genetic screening for donor-recipient genetic matching. The importance of pre- and post-screening genetic counselling, the management of the occurrence of adverse reactions of a genetic nature and the use of informed consent from donors who accept the management of their DNA samples stored in the centre's bank are emphasized. The role of informed consent to find out patients’ opinions on what type of screening they want to be carried out, their desire to know the results of the screening and aptitude for future genetic data is also highlighted.