One-Pot Thiourea Formation–Palladium-Catalyzed Cyclization Sequence to 3,4-Dihydro-2H-1,3-benzothiazine-2-imines from 2-Halo N-Methylbenzyl­amine – Scope and Limitations

A practical synthesis of 3,4-dihydro-3-methyl-2 H -1,3-benzothiazine-2-imine via intramolecular palladium-catalyzed C–S bond formation is presented and exemplified for both alkyl- and ­arylisothiocyanates.