Dietary polyphenols inhibit the cytochrome P450 monooxygenase branch of the arachidonic acid cascade with remarkable structure-dependent selectivity and potency

The products of the cytochrome P450 monooxygenase (CYP)-catalyzed oxidation of arachidonic acid (AA), i.e. epoxy- and hydroxy-fatty acids, play a crucial role in the homeostasis of several physiolo...