P2609 Distribution of respiratory manifestations during the chlamidiaee psittaci infections

Aims: To evaluate Legionella urinary antigen detection in relation to the complications in L. pneumophila CAP. Methods: A prospective multicenter study over 1,314 CAP was carried out in 10 hospitals during 12-month period. Aetiological diagnosis was established by serological tests, pleural and blood cultures, L. pneumophila and S. pneumoniae urinary antigen tests. Results: An aetiological diagnosis was obtained 579 cases (44.1%) and L. pneumophila was found in 154 (26.6%) of them. Using Pneumonia Severity Index (PSI) risk classes: 47 (30.5%) belonged to classes I, II, 42 (27.3%) to class III and 65 patients (42.2%) to classes IV, V. Overall hospital admission was high, 136 (89.6%), even in low risk classes (I, II), 35 (74.5%) although they were significantly lower than in higher risk classes (IV, V), 64 patients (98,5%) (p=0,01). L. pneumophila was diagnosed by urinary antigen (UA) in 86 cases and in 65 of them by serology too. Serology was the only diagnosis method in 68 cases (44,2%) mainly applied in outpatients. UA test positivity rate was higher in groups III, IV,V (91,6%), than in I, II (74,5%) (p=0,03). Complications were similar in both groups (26 patients): I, II: 4 (2,6%), III, IV, V: 22 (20,5%) (p=0,06). The mortality was low 3,2% (5 cases in high risk classes) Conclusion: Legionella urinary antigen detection established diagnosis more in high risk classes than in the lower ones We didn’t find differences regarding complications between high and low risk classes, probably due to the number of patients of our study