Isophenoxazine Synthase Model. Oxidation of o-Aminophenol by an Oxidation-Active Flavin Mimic in an Aqueous Solution

It was found that a flavin mimic, benzo-dipteridine (BDP), oxidizes o-aminophenol in an aqueous solution under anaerobic conditions. Under aerobic conditions, 2-aminophenoxazine-3-one was isolated. This is the first example of an isophenoxazine synthase model.