Bowel Ultrasound Scan Predicts Corticosteroid Failure in Children With Acute Severe Colitis

BACKGROUND AND OBJECTIVE: Acute Severe Colitis (ASC) is a potentially life-threatening event. Optimal timing for second-line treatment in children is mainly based on the clinical score PUCAI. The aim of our study was to evaluate the potential role of bowel ultrasound scan (BUS) in predicting the need of second-line therapy in ASC. METHODS: Patients aged 3.4 mm) and loss of CWS as independent predictors of steroid-resistance. CONCLUSIONS: BUS is a non-invasive, easily accessible and cost-effective resource that may identify at an early stage first-line therapy failure in pediatric ASC.