Intrathoracic extramedullary hematopoietic tumor in hemoglobin C disease

. A case of intrathoracic extramedullary hematopoietic tumor associated with hemoglobin C disease is reported in a 27-year-old Bangladeshi man. The patient's initial complaints were generalized weakness, weight loss, and left upper abdominal pain. Hospital workup revealed a solitary intrathoracic mass in the posterior mediastinum, which was suspected to be a lymphoma based on fine-needle aspiration. The mass was excised and proved to be an extramedullary hematopoietic tumor. The problem of differential diagnosis is discussed.