Localised chronic eyelid disease resulting from long term hydroxyurea therapy

Editor,—Hydroxyurea is an antineoplastic agent used in the treatment of various myelproliferative conditions and severe psoriasis. Documented skin manifestations from long term therapy with hydroxyurea include icthyosis, a dermatomyositis-like eruption on the dorsal hands, facial erythema, and accelerated development of premalignant and malignant skin lesions.1-5 Our patient is the first described case of a cutaneous manifestation of long …