Pharmaceutical combination with stable strontium ranelate and its preparations

The invention discloses a drug composite to promote the stability of strontium ranelate in the preparation. The invention is characterized in that after the effective dosage of the strontium ranelate for treatment is mixed with medicinal excipients, various dosage forms are produced by adding stabilizer. The dosage of the stabilizer refers to the dosage scope of excipients proscribed in the pharmacopoeia. The experiments and studies determine that the weight percentage of the stabilizer in the drug composite is 0.01-5 percent, which is preferred as 0.01-2 percent. The invention with a simple and unique way solves the color change problem of appearance of strontium ranelate or the problem of material increasing resulting from the excipients like citric acid, aspartame and saccharin sodium contained in the preparation; under the condition of not changing the structure of the strontium ranelate, a certain dosage of stabilizer is added into the excipients to achieve the purpose of the stability of the strontium ranelate. The method simplifies the process and saves the cost, and is more suitable for large-scale industrial production.