Nocturnal sleep and daytime physical activity in patients with ILD: Preliminary results

Background: Sleep disturbances are common in patients with interstitial lung disease (ILD). It remains unclear whether sleep quality interferes on the physical activity in daily life (PADL). Aims: To investigate the association between nocturnal sleep measurements and the PADL of the following day in ILD and control subjects. Methods: 16 patients with ILD (59±7years, 9 men) and 10 healthy subjects (66±11years, 4 men) were recruited and submitted to the assessments of sleep and PADL by an activity monitor (Actigraph®). PADL and sleep were correlated (Spearman coefficient) and compared (Mann-Whitney) between groups. Results: 129 days (ILD, n=74; control, n=55) were analysed. Patients presented worse PADL and nocturnal sleep in relation to the control group (Table 1). Sleep efficiency was strongly correlated with number of nocturnal awakening (r=−0.67) and wakefulness after sleep onset (r=−0.76). Nocturnal sleep duration was moderately correlated with time in activities of light intensity(r=−0.56) and steps (r=−0.44). Table 1 - Comparisons of PADL and sleep between groups *p Conclusion: Sleep measurements and PADL are related in patients with ILD. Identifying groups with sleep disturbances can be useful when designing interventions to improve PADL.