Research progress on protein-energy wasting in patients with chronic kidney disease

Patients with chronic kidney disease often experience protein-energy wasting.The clinical manifestations performs include the abnormality of nutrient intake,biochemical index,body mass index,and muscle mass.Protein-energy wasting always results from decreased dietary intake,inflammation,metabolic acidosis,hormone level disorder,dialysis related factors,social psychological factors and so on,and seriously affects the prognosis and survival rates of patients with chronic kidney disease.Therefore,early detection,diagnosis and prevention and cure are very important.Nutritional evaluation should be included in daily diagnosis and treatment in patients with chronic kidney diseases.Contrasting diagnostic criteria,prevention and control of protein-energy wasting with early diagnosis and taking various measures will improve the prognosis and survival rate of patients with chronic kidney disease ultimately.Thus,the aim is to improve the patients' understanding of epidemiological characteristics,pathogenesis,assessment,treatment and intervention measures of protein-energy wasting in patients with chronic kidney disease. Key words: Protein-energy wasting;  Chronic kidney disease