6. The Double Blind Studies of Bromelain for the Patients following Surgical or Cryosurgical Hemorrhoidectomy

The double blind studies of bromelain for 161 patients following surgical or crvosurgical hemorrhoidectomy were performed.Every patient was apllied bromelain or placebo tablets orally, every two tablets, three times daily and seven-days duration.Scoring number for the postoperative focal inflammatory symptoms (1. swelling, 2. pain, 3. secretion and 4. bleeding) of every patient was recorded and finally all records were col-lected and analyzed.1. Statistical differences were recognized as follows:a) Ligation and excision group : 7 th day's secretion score, 10 th day's secretion score, loth day's total score, and case-ratio of pain from 1 st to 3rd day changeb) Cryosurgery group : 3rd day's bleeding score, and score-ratio of bleeding from 3 rd to 5th day change2. Moderate, but not statistical differences were noticed as follows:a) Ligation and excision group : 10th day's pain score, secretion total score, and 7th day's total scoreb) Cryosurgery group : score-ratio of pain from 3rd to 5th day change, and score-ratio of scretion from 1st to 3rd changeAs above results, it is thought that apllication of bromelain tablets for surgical hemor-rhoidectomy patients is favorable.Suitability of post-hemorrhoidectomy patients for bromelain double blind studies and reasonable selection of parameters were discussed.