Identification of novel fatty acid glucosides from the tropical fruit Morinda citrifolia L.

Abstract Two new fatty acid glucosides, 1,6-di- O -octanoyl-β- D -glucopyranose ( 1 ) and 6- O -(β- D -glucopyranosyl)-1- O -decanoyl-β- D -glucopyranose ( 2 ), were isolated from a methanol extract of the fruit of Morinda citrifolia L. along with five known saccharide fatty acid esters. The structures of these compounds were determined by combination of spectral and chemical analyses. These fatty acid glucosides exhibited inhibitory effect against copper-induced low-density lipoprotein oxidation. Compound 2 had the strongest effect, which was almost comparable to that of butylated hydroxytoluene.