Effect of Low-Intensity Blue Light Emission on Physicochemical Properties of Blood Erythrocytes in Rats under Diabetes Mellitus Conditions

Abstract—The physicochemical characteristics of erythrocyte membranes from the peripheral whole blood of rats and the erythrocytes washed with physiological solution, using the method of acid hemolysis, under diabetes mellitus conditions and against the therapy based on low-intensity blue light emission in the visible light range have been studied. The use of low-intensity light therapy (LILT) led to a decrease in the resistance of erythrocyte membranes to the action of acid hemolytic in the control group animals. Under diabetes conditions, LILT prolonged total hemolysis and reduced the count of hemolysed erythrocytes relative to the indices in the group of animals with DM. No expressed hypoglycemic effect due to the LILT was observed in sick animals, and the content of glycolysed hemoglobin tended to decrease.