Alamandine enhances cardiomyocyte contractility in hypertensive rats through a NO-dependent activation of CaMKII.

Itamar Couto Guedes de Jesus,Thássio Ricardo Ribeiro Mesquita,André Luís Lima Monteiro,Amanda B. Parreira,Anderson K. Santos,Elizeu Lucas Xavier Coelho,Mario de Morais e Silva,Lucas A. C. Souza,Maria José Campagnole-Santos,Robson Augusto Souza Dos Santos,Silvia Guatimosim

Alamandine enhances cardiomyocyte contractility in hypertensive rats through a NO-dependent activation of CaMKII.

2020

Itamar Couto Guedes de Jesus
Thássio Ricardo Ribeiro Mesquita
André Luís Lima Monteiro
Amanda B. Parreira
Anderson K. Santos
Elizeu Lucas Xavier Coelho
Mario de Morais e Silva
Lucas A. C. Souza
Maria José Campagnole-Santos
Robson Augusto Souza Dos Santos
Silvia Guatimosim

Overstimulation of the renin-angiotensin system (RAS) has been implicated in the pathogenesis of various cardiovascular diseases. Alamandine is a peptide newly identified as a protective component ...

Keywords:

Cell biology
Biochemistry
Alamandine
Biology
Ca2+/calmodulin-dependent protein kinase
Contractility
Pathogenesis
ventricular myocytes
Peptide
Nitric oxide
Stimulation

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