Exendin stable aqueous pharmaceutical composition needle

The present invention discloses a multi-dose exendin use water injection and a pharmaceutical composition pharmaceutical composition, wherein the method according to the present invention can be long-term storage of formulations exendin. The pharmaceutical compositions of the invention include: exendin, exendin analogs and derivatives thereof; pharmaceutically acceptable tonicity adjusting agent (stabilizer); pharmaceutically acceptable preservative; pharmaceutically acceptable chaotropic agents and a pharmaceutically acceptable buffer solution. Insulinotropic secretory peptide of the present invention can be used in pharmaceutical compositions medicament for the treatment of diabetes and obesity.