The Medtronic Minimed Gold continuous glucose monitoring system: an effective means to discover hypo- and hyperglycemia in children under 7 years of age.

Background: The glycemic patterns of children less than 7 years with type 1 diabetes have not been well studied using continuous glucose monitoring. Our goal was to assess the incidence of hypoglycemia as well as postprandial glycemic patterns in this age group utilizing continuous glucose monitoring. Methods: Nineteen children used the Medtronic MiniMed (Northridge, CA) CGMS® System Gold™ on three to seven occasions over approximately 6 months. Results: Nineteen children (nine girls and 10 boys; mean age 4.8 ± 1.4 years, range 1.6–6.8 years) used the CGMS 102 times, providing 434 days of data; 79% of days were optimal based on CGMS Solutions software version 3.0. Mild hypoglycemia (glucose ≤70 mg/dL) was noted during 28% of 323 nights. When compared to paired meter blood glucose values, the false-positive rate was 16% for mild and 55% for severe sensor hypoglycemia. The mean peak glucose during the 3 h following breakfast (247 ± 64 mg/dL) was higher than following lunch (199 ± 67 mg/dL) or dinner (194 ± ...