Exploring space-energy matching via quantum-molecular mechanics modeling and breakage dynamics-energy dissipation via microhydrodynamic modeling to improve the screening efficiency of nanosuspension prepared by wet media milling.

Jing Tian,Fangxia Qiao,Yanhui Hou,Bin Tian,Jianhong Yang

Exploring space-energy matching via quantum-molecular mechanics modeling and breakage dynamics-energy dissipation via microhydrodynamic modeling to improve the screening efficiency of nanosuspension prepared by wet media milling.

2021

Jing Tian
Fangxia Qiao
Yanhui Hou
Bin Tian
Jianhong Yang

Introduction: The preparation of nanosuspensions by wet media milling is a promising technique that increases the bioavailability of insoluble drugs. The nanosuspension is thermodynamically unstabl...

Keywords:

Molecular mechanics
energy matching
Quantum
Chemical physics
crystal morphology
Dynamics (mechanics)
Breakage
Space (mathematics)
Materials science
Dissipation

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