Pruritus treatment agent
2008
The present inventors have found that from a human antibody phage library, in the IL-31-dependent Ba / F3 cell proliferation assay system, a clone was obtained BM095 exhibiting strong growth-suppressing activity. Using this anti-mouse NR10 neutralizing antibody, was administered to pruritus model mice, it showed the effect of suppressing noticeable symptoms. Anti NR10 neutralizing antibody is found to be useful as pruritus treatment.
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