Comparison of Long-term Outcome Between White and Vietnamese children Treated for Acute Lymphoblastic Leukemia According to the FRALLE 2000 protocol

Several factors may contribute to the poor RFS in Vietnamese children, which include the time interval before the first intrathecal therapy and differences in the management of drug-related toxicity. However, additional contribution of socioeconomic factors and/or variations in pharmacogenetic polymorphisms in Vietnamese patients cannot currently be ruled out.