Bioavailability of ampicillin preparations for internal use

: Bioavailability of various ampicillin dosage forms was studied. No difference in the level and rate of the antibiotic absorption was observed with the use of ampicillin trihydrate and anhydrous ampicillin capsules and ampicillin trihydrate tablets. Significant differences in the rate of ampicillin transfer into solution from various dosage forms were noted in the studies with the "rotating basket" apparatus. No correlation between the rate of ampicillin transfer into solution and the level of ampicillin absorption was found.