Applications of neural network analyses to in vivo 1H magnetic resonance spectroscopy of epilepsy patients
1999
Abstract A total of 67 in vivo water-suppressed proton magnetic resonance spectra of the temporal lobes were recorded from 15 patients with long standing temporal lobe epilepsy and 13 healthy volunteers. Conventional data analysis indicated slightly lower N -acetyl aspartate levels in epileptic patients compared with controls. For further analysis of data, a spectral region (4.0–1.5 ppm) was used as input for artificial neural network analysis. Correct classification of spectra was obtained in 66 out of 67 cases, disregarding from which side of the brain the spectra were recorded. The ability of the trained network to recognize spectra recorded both contalaterally and ipsilaterally to the epileptic focus strongly indicates bilateral metabolic changes. Artificial neural networks could also be trained to recognize whether the spectra were recorded from the ipsilateral or contralateral side of the epileptic focus, indicating that neural network analysis of in vivo proton MR spectra can be used as an additional tool for pre-surgical lateralization of seizure foci.
Keywords:
- Nuclear magnetic resonance spectroscopy
- Temporal lobe
- Epilepsy
- In vivo magnetic resonance spectroscopy
- Psychology
- Artificial neural network
- Anesthesia
- Lateralization of brain function
- Magnetic resonance imaging
- Artificial intelligence
- Pattern recognition
- Nuclear magnetic resonance
- Central nervous system disease
- In vivo
- Focus (geometry)
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
19
References
20
Citations
NaN
KQI