Urinary biomarkers of oxidative stress and breast cancer survival

Purpose Systemic oxidative stress has been implicated in the pathogenesis and progression of many chronic diseases, including breast cancer. No studies have investigated F2-isoprostanes (F2-IsoPs), valid biomarkers of systemic oxidative stress, in association with breast cancer prognosis. We conducted a nested case–control study in a prospective breast cancer survivor cohort to investigate systemic oxidative stress and survival.