Imaging dynamics of CD11c(+) cells and Foxp3(+) cells in progressive autoimmune insulitis in the NOD mouse model of type 1 diabetes

Anja Schmidt-Christensen,Lisbeth Hansen,Erwin Ilegems,Nina Fransén-Pettersson,Ulf Dahl,Shashank Gupta,Åsa Larefalk,Tine D. Hannibal,Alexander Schulz,Per-Olof Berggren,Dan Holmberg

Imaging dynamics of CD11c(+) cells and Foxp3(+) cells in progressive autoimmune insulitis in the NOD mouse model of type 1 diabetes

2013

Anja Schmidt-Christensen
Lisbeth Hansen
Erwin Ilegems
Nina Fransén-Pettersson
Ulf Dahl
Shashank Gupta
Åsa Larefalk
Tine D. Hannibal
Alexander Schulz
Per-Olof Berggren
Dan Holmberg

Aims/hypothesis The aim of this study was to visualise the dynamics and interactions of the cells involved in autoimmune-driven inflammation in type 1 diabetes.

Keywords:

Inflammation
Type 1 diabetes
Insulitis
FOXP3
Immunology
Islet
Transplantation
Endocrinology
Nod
Diabetes mellitus
Internal medicine
Biology
Pancreas
CD11c
Beta cell
Immune system

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