Negative sliding sign during dynamic ultrasonography predicts low endometriosis fertility index at laparoscopy.

ABSTRACT Study Objectives Endometriosis fertility index (EFI) is a robust tool to predict pregnancy rate in endometriosis patients who are attempting non-in vitro fertilization conception. However, EFI calculation requires laparoscopy. Newly established imaging techniques such as sliding sign, that is used to diagnose Pouch of Douglas obliteration, could provide a promising alternative. The objective of this study is to investigate the practicality of using ultrasound data to predict low EFI (score ≤6). Design Observational study from a prospective registry (Endometriosis Pelvic Pain Interdisciplinary Cohort (EPPIC), ClinicalTrials.gov#NCT02911090). Analyzed data was captured from December 2013 to June 2017. Setting Tertiary referral center at British Columbia Women's Hospital. Patients or Participants We analyzed data for 2583 participants from EPPIC. In this cross-sectional study, we included eighty-six women who are less than 40 years old. Interventions Dynamic ultrasonography for the sliding sign testing and EFI calculation during laparoscopic surgery Measurements and Main Results Logistic regression was used to obtain ROC area under the curve (AUC) for the prediction models. Significance was p Conclusion The sliding sign could be a potential alternative to the EFI surgical factors, and it could be used in combination with EFI historical factors and the diagnosis of endometrioma to predict an EFI score ≤6 for patients who are not scheduled for immediate surgery.