Pathogen detection of 1 613 cases of hospitalized children with community acquired pneumonia

Objective To investigate the distribution of pathogens of children with community acquired pneumonia(CAP) from the Chongqing area. Methods Nasopharyngeal specimens and blood specimens of 1 613 children with CAP were collected between January 2014 and December 2014 for bacterial culture and detection of 7 respiratory viruses and antibodies against Mycoplasma pneumoniae(MP). Results The overall positive rate of bacteria was 50.22%(810 cases). Hemophilus parainfluenzae(40.8%), Streptococcus pneumonia(29.7%) and Moraxelle catarrhalis(7.3%) were the predominant ones. Among the viruses, the top detected virus was respiratory syncytial virus(RSV, 58.3%), followed by parainfluenza virus type3(17.4%) and adenovirus(14.3%). A total of 481 cases(29.82%) were MP-positive. The co-infection rate was 32.18%(519 cases), and the mixed infections of bacteria and viruses were common(47.4%). Conclusions RSV and Hemophilus parainfluenzae are the major pathogens of CAP in children from the Chongqing area. MP is also an important pathogen. The co-infection of bacteria and viruses is prevalent.