Sa1642 Gastric Epithelial Dysplasia: Characterization and Long-Term Follow up Results According to Morphological Categorization

On each line: pCLE image representative of a query video (framed image on the left), followed by 3 pCLE images representative of the 3 atlas videos which have been automatically recognized by the Smart Atlas software as the most visually similar to the query video. Each pCLE video is annotated with final diagnosis. Sa1641 Synchronous and Metachronous Multiple Gastric Tumors After Endoscopic Submucosal Dissection Yoo Jin Lee*, Kwangbum Cho, Kyung Sik Park, Eun Soo Kim, Eun Sung Choi, Jung MIN Lee, Yu Jin Kang, Sang MIN Lee Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea Background/Aims: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of gastric tumor. The study was aimed to investigate the incidence and characteristics of multiple gastric tumors after ESD. Methods: Patients with gastric tumors treated by ESD from January 2004 through June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were treated with subsequent ESD method and their medical records were reviewed retrospectively. Results: A total of 655 patients were included. The mean period of endoscopy follow-up was 32.89 23.28 months (12-107). Overall 126 patients (19.2%) showed multiple gastric tumors during follow up period (synchronous 46 (7.0%) and metachronous 80 (12.2%)). The annual incidence of multiple gastric tumor was approximately 13.7%. The number of differentiated type cancer was 64 (50.8%), undifferentiated type 6 (4.8%), and adenoma 56 (44.4%). Over half of tumors developed at the same longitudinal location of the stomach, showed the same macroscopic type, and revealed the same histological type as the primary lesions. Old age and concomitant Helicobacter pylori infection appeared to be related with the development of metachronous gastric tumors. Conclusions: As synchronous and/or metachronous gastric tumors are not uncommon, a considerable attention should be paid to discover multiple gastric lesions after ESD. AB286 GASTROINTESTINAL ENDOSCOPY Volume 79, No. 5S : 2014 Sa1642 Gastric Epithelial Dysplasia: Characterization and Long-Term Follow up Results According to Morphological Categorization Dong Hoon Baek*, Gwang HA. Kim, Bong Eun Lee, Hyun Jeong Lee, Joon Hyung Jhi, Dong UK. Kim, Geun Am Song Internal Medicine, Gastroenterology, Pusan National University Hospital, Busan, Republic of Korea Background: Gastric epithelial dysplasia (GED) can be morphologically categorized into adenomatous, foveolar and hybrid types, but there are few studies on the clinical and endoscopic characteristics in the types of GED, especially assessing their correlation with long term outcome after endoscopic resection. The aims of this study were to elucidate clinicopathological characteristics and long term follow-up results according to each type of GEDs after endoscopic resection. Methods: From January 2008 to December 2009, 357 patients who underwent endoscopic resection of GEDs at Pusan National University Hospital were studied. Retrospectively, comparisons of clinicopathological characteristics including endoscopic findings between the types of GED were assessed and long term follow-up data (synchronous, metachronous lesions and detection of gastric cancer after endoscopic resection) were evaluated. Results: Adenomatous type made up the biggest proportion, 46.8%, followed by 28.9% for foveolar type. The foveolar type of GEDs was significantly more likely than adenomatous type to show endoscopically located on antrum, flat/ depressed lesion, reddish in color, and to reveal histopathologically high grade dysplasia. In the long term follow-up results, adenomatous type was of synchronous lesions significantly more often than foveolar and hybrid type (pZ 0.013). However, there were no significant differences among the types in terms of the metachronous, and detection of gastric cancer during a median follow-up period of 41.1 months (range, 12-69.5 months) after endoscopic resection. Conclusions: In our study of endoscopically resected GEDs, GEDs have different clinicopathological characteristics as well as long-term follow up results according to each subtype. Clinicopathological and Endoscopic characteristics according to morphological types of GED Adenomatous type (n [ 167) Foveolar type (n [ 103) Hybrid type (n[87) www.giejourna p value