Antiproliferative activity of morpholine-based compounds on MCF-7 breast cancer, colon carcinoma C26, and normal fibroblast NIH-3T3 cell lines and study of their binding affinity to calf thymus-DNA and bovine serum albumin

Mahboubeh Hosseini-Kharat,Rahmatollah Rahimi,Davit Zargarian,Zohreh Mehri Lighvan,Amir Abbas Momtazi-Borojeni,Tayebeh Sharifi,Elham Abdollahi,Hossein Tavakol,Tecush Mohammadi

Antiproliferative activity of morpholine-based compounds on MCF-7 breast cancer, colon carcinoma C26, and normal fibroblast NIH-3T3 cell lines and study of their binding affinity to calf thymus-DNA and bovine serum albumin

2018

Mahboubeh Hosseini-Kharat
Rahmatollah Rahimi
Davit Zargarian
Zohreh Mehri Lighvan
Amir Abbas Momtazi-Borojeni
Tayebeh Sharifi
Elham Abdollahi
Hossein Tavakol
Tecush Mohammadi

AbstractThis report describes the results of a study on the antiproliferative activity of the morpholine-based ligand 1,3-bis(1-morpholinothiocarbonyl)benzene (HL) and its nickel(II) complex (NiL) ...

Keywords:

Breast cancer
Molecular biology
Carcinoma
Bovine serum albumin
DNA
Morpholine
Fibroblast
Ligand (biochemistry)
Cell culture
Chemistry
Ligand
Viability assay
MCF-7

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