Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells

Shang Shang Gao,Byung-Min Choi,Xiao Yan Chen,Ri Zhe Zhu,Youngho Kim,Hong Seob So,Raekil Park,Meesook Sung,Bok-Ryang Kim

Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells

2010

Shang Shang Gao
Byung-Min Choi
Xiao Yan Chen
Ri Zhe Zhu
Youngho Kim
Hong Seob So
Raekil Park
Meesook Sung
Bok-Ryang Kim

Purpose The present study was undertaken to elucidate the chemoprotective mechanism of kaempferol, which possesses anti-oxidative and anti-apoptotic properties.

Keywords:

Heme oxygenase
Cisplatin
Glutathione
Chemoprotective
Apoptosis
Programmed cell death
GCLC
Biochemistry
Chemistry
Kaempferol

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