Tricyclic derivatives of n, n'-substituted 3,7-diazabicyclo [3.3.1] nonanes having pharmacological activity, and drugs based on their

1. Tricyclic derivatives of N, N'-substituted 3,7-diazabicyclo [3.3.1] nonanes having pharmacological activity, general formula 1: ! wherein HM is hereinafter pharmacologically acceptable acid; ! X represents a carbonyl group, a methylene group, OH; ! R1 and R'1 are the same or different and each independently represents H, C1-C6 alkyl, C1-S10alkoksi; ! R2 collectively represented by the general formulas (1.1a), (1.2a), (1.3a), (1.4a): ! ! !! R3 ', R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'9, R10, R'10, R11, R'11 , R15 and R'15 may be the same or different and each independently represents H, C1-C6 alkyl, C1-S10alkoksi; ! R12 represents C1-C6 alkyl; ! R13 and R13 'may be the same or different and each independently represents H, C1-C6 alkyl, C1-C10 alkoxy, hydroxy, halogen, amino, nitro, nitrile, acyl, aryl; ! Z is N, CH; ! E is N, or a group of the general formula: ! wherein n = 1-3; R14 is H, C1-C6 alkyl, C1-C10 alkoxy, hydroxy; ! Y represents - (CR16R'16) m-, wherein m = 1-3; ! R16 and R'16 may be the same or different and each independently represents H, C1-C6 alkyl, C1-C10 alkoxy; ! 2. Compounds according to claim 1, representing the tricyclic derivatives of N, N'-substituted 3,7-diazabicyclo [3.3.1] nonanes of general formula (1.1): ! in which HM is hereinafter pharmacologically acceptable acid; ! E, Z, R1, R3, R3 ', R4, R4', X, R5, R5 ', R6, R6', R7, R7 ', R8, R8', R12, R13, R13 ', R15 and R15' are as defined above for formula 1! 3. Compounds according to claim 1, representing the tricyclic derivatives of N, N'-substituted 3,7-diazabicyclo [3.3.1] nonanes of general formula (1.2): ! in which MI hereinafter represents a pharmacologically acceptable acid; ! E, Z, R1, R3, R3 ', R4, R4', X, Y, R5, R5 ', R6,