Pathological features and prognosis in chronic hepatitis B virus carriers.

who were hepatitis B e antigen (HBeAg)positive. Abnormal inflammation ( ≥ G 2 ) occurred in 122 (55.5%) patients. Hepatitis B reactivation occurred in 35 (15.9%) patients: 33 had obvious liver inflammation at the initial biopsy ( ≥ G 2 ) and only two had a low level of liver inflammation (G 0 ‐ G 1 ). The hepatitis B reactivation rate was significantly related to age but not to gender. Hepatitis B surface antigen clearance was 1.55% per year and HBeAg seroconversion was 5.36% per year. In conclusion, hepatitis B reactivation was closely correlated with age and the level of liver inflammation.