Factors Associated with the Risk of Adenoma Recurrence in Distal and Proximal Colon

years (RRR = 1.47, 95% CI 1.00–2.16), age ≥ 70 years (RRR = 2.24, 95% CI 1.57–3.20), and male sex (RRR = 1.73, 95% CI 1.32–2.27) were positively associated with proximal only adenoma recurrence. NSAIDs use was associated with a reduced risk of adenoma recurrence by similar magnitude in distal (RRR = 0.78, 95% CI 0.58–1.07) and proximal colon (RRR = 0.77, 95% CI 0.60–1.00). Conclusions: We did not find any modifiable risk factor that differentially increases proximal as compared to distal adenoma recurrence to be clinically useful for targeted intervention.