Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics.

Yi Gu,Jian Wang,Ke Li,Li Zhang,Hongcan Ren,Lixia Guo,Yang Sai,Weihan Zhang,Weiguo Su

Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics.

2014

Yi Gu
Jian Wang
Ke Li
Li Zhang
Hongcan Ren
Lixia Guo
Yang Sai
Weihan Zhang
Weiguo Su

Purpose This study evaluated the preclinical pharmacokinetics (PK) and disposition of Fruquintinib (HMPL-013), a small molecule vascular endothelial growth factor receptors inhibitor.

Keywords:

Small molecule
Pharmacology
VEGFR Inhibitor
Fruquintinib
Vascular endothelial growth factor
Disposition
Pharmacokinetics
Receptor
Medicine
preclinical pharmacokinetics

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations