Breakthrough viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients receiving levofloxacin prophylaxis in a Japanese hospital

Muneyoshi Kimura,Hideki Araoka,Atsushi Yoshida,Hisashi Yamamoto,Masahiro Abe,Yuki Okamoto,Mitsuhiro Yuasa,Daisuke Kaji,Kosei Kageyama,Aya Nishida,Kazuya Ishiwata,Shinsuke Takagi,Go Yamamoto,Yuki Asano-Mori,Naoyuki Uchida,Akira Hishinuma,Koji Izutsu,Atsushi Wake,Shuichi Taniguchi,Akiko Yoneyama

Breakthrough viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients receiving levofloxacin prophylaxis in a Japanese hospital

2016

Background Breakthrough viridans streptococcal bacteremia (VSB) in patients with hematological malignancy receiving levofloxacin prophylaxis is a major blood stream infection (BSI) occurring during febrile neutropenia. However, clinical data focused on VSB in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients are lacking.

Keywords:

Virology
Levofloxacin
Hematopoietic stem cell transplantation
Transplantation Conditioning
Febrile neutropenia
Medical microbiology
Medicine
Bacteremia
Antibiotic prophylaxis
Immunology
Viridans streptococci
Internal medicine
Surgery
Piperacillin
Cefepime
Tazobactam

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