DNA hydroxymethylation increases the susceptibility of reactivation of methylated P16 alleles in cancer cells
2019
ABSTRACTIt is well established that 5-methylcytosine (5mC) in genomic DNA of mammalian cells can be oxidized into 5-hydroxymethylcytosine (5hmC) and other derivates by DNA dioxygenase TETs. While c...
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