Reader response: Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis

2019 
We read the article by Pfuhl et al. 1 with interest. Our group demonstrated that intrathecal oligoclonal IgM bands (OCMB) were a risk factor for early conversion to MS2 and also for increase in T2 lesions and early brain atrophy on magnetic resonance.3
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