5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists

Stephen J. Fowler,Ian P. Hall,Andrew Wilson,Amanda Wheatley,Brian J. Lipworth

5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists

2002

Stephen J. Fowler
Ian P. Hall
Andrew Wilson
Amanda Wheatley
Brian J. Lipworth

Objective. To determine whether genetic polymorphisms of the core promoter region of the 5-lipoxygenase gene contribute to the clinical response to leukotriene receptor antagonists.

Keywords:

Wild type
Arachidonate 5-lipoxygenase
Leukotriene Receptor Antagonists
In vivo
Polymorphism (computer science)
Genotype
Gene
Pharmacology
Chemistry
Promoter
Leukotriene receptor
Population
Medicine
Antagonist
Adenosine monophosphate
Bronchial hyperresponsiveness

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