Experimental Osteoarthritis in Rats Is Attenuated by ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Leo R. Fitzpatrick,Cecelia L. Green,Lynn W. Maines,Charles D. Smith

Experimental Osteoarthritis in Rats Is Attenuated by ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

2011

Leo R. Fitzpatrick
Cecelia L. Green
Lynn W. Maines
Charles D. Smith

Background/Aims: Osteoarthritis (OA) is a progressive degenerative disease characterized by cartilage degradation and chondrocyte apoptosis, which may involve aberrant sphingolipid

Keywords:

Osteoarthritis
Cartilage
Endocrinology
Chondrocyte
Internal medicine
Degenerative disease
Sphingosine Kinase 2
Immunology
Apoptosis
Sphingosine kinase
Sphingolipid
Pharmacology
Chemistry
Diabetes mellitus

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