Case 21-2004

This patient presented at the age of 55 years with prostate cancer, detected because of urinary symptoms and a rising prostate-specific antigen (PSA) level. He was well for seven years after local radiation therapy and androgen-deprivation treatment; then his PSA level began to rise, and metastatic lesions were detected. The care of this patient necessitated consideration of treatment options for patients with localized and advanced prostate cancer and hormone-refractory disease.